| 摘要 |
The invention concerns compounds of formula (I) wherein:Ar represents a mono- or disubstituted phenyl;Rrepresents a phenyl that is unsubstituted or substituted once or twice with a halogen atom;Rrepresents: a pyridyl; a phenyl that is un-substituted or substituted once or twice with one or two substituents independently chosen from a halogen atom, a (C-C)alkyl, a (C-C)alkoxy, a trifluoromethyl group and a trifluoromethoxy group;besides, Rmay also represent: a heterocyclic radical chosen from azetidine, pyrrolidine, piperidine, morpholine, thiomorpholine or perhydroazepine when Rrepresents a group –CONRR;Rrepresents a group chosen from:(5) -(CH)-OH, in which q is 0;(10) -(CH)-NRCOR, in which q is 0;(11) -(CH)-NROOR, in which q is 0;(18) –CONRR.The invention also concerns a method for preparing said derivatives and their therapeutic use. |
