| 发明名称 |
ASYMMETRIC SYNTHESIS OF PREGABALIN |
| 摘要 |
<p>The invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorder, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.</p> |
| 申请公布号 |
BG65560(B1) |
申请公布日期 |
2008.12.30 |
| 申请号 |
BG20020106849 |
申请日期 |
2002.06.20 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
BURK MARK;GOEL OM;HOEKSTRA MARVIN;MICH THOMAS;MULHERN THOMAS;RAMSDEN JAMES |
| 分类号 |
C07C227/10;C07B53/00;C07B61/00;C07C227/04;C07C229/08;C07C253/30;C07C255/19;C07C255/23 |
主分类号 |
C07C227/10 |
| 代理机构 |
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