摘要 |
FIELD: chemistry, pharmacology. ^ SUBSTANCE: invention relates to novel compound - acetone solvate of 4-acetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1-hydroxy-7beta, 10beta-dimethoxy-9-oxo-tax-11-ene-13alpha-yl-(2R,3S)-3-tretbutoxycarbonylamino-2-hydroxy-3-phenylpropionate, containing from 5 to 7 wt % of acetone, which has anti-cancer and anti-leukaemia activity, and method of obtaining it by crystallisation in water-alkali solution. ^ EFFECT: obtaining valuable biologically active compound in such form that allows obtaining standard medicinal forms. ^ 5 cl, 1 dwg, 1 ex |