发明名称 PROGNOSTIC METHOD FOR COMPLICATED PHLEGMON CLINICAL COURSE
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to the field of medicine. Prognostic method is based, on one hand, on integral indices of macroorganism condition, and on other hand, on microorganism pathogenicity factors. In soft tissue phlegmonic patients, presence and intensity of system inflammatory response syndrome is evaluated. From biomaterial in the nidus of surgical infection, the pure pathogen culture is isolated, its species is identified, its virulent and persistent characteristics are determined, and risk of local purulent complication development is calculated by formula R=-5.699x1-3.828x2-6.210x3-2.525x4-5.699x5-2.495x6-3.066x7-3.703x8; if R>=0, the prognosis is favourable, if R<0, local purulent complication development is prognosticated. In case of unfavourable prognosis, pathogen elimination period is determined by formula y=0.638x+1.06, where y is pathogen elimination period, x is pathogen anticomplementary activity level. ^ EFFECT: providing objectivity and reproducibility; allowing timely risk evaluation of local purulent complication development. ^ 1 dwg, 2 ex
申请公布号 RU2342656(C2) 申请公布日期 2008.12.27
申请号 RU20070100763 申请日期 2007.01.09
申请人 GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "ORENBURGSKAJAMEDITSINSKAJA AKADEMIJA FEDERAL'NOGO AGENTSTVA POZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU" (GOU VPO ORGMA ROSZDRAVA);INSTITUT KLETOCHNOGO I VNUTRIKLETOCHNOGO SIMBIOZAURAL'SKOGO OTDELENIJA ROSSIJSKOJ AKADEMII NAUK 发明人 MALITSKAJA ELENA VLADIMIROVNA;FADEEV SERGEJ BORISOVICH;GLAZEVA SVETLANA ANATOL'EVNA;BUKHARIN OLEG VALER'EVICH;TARASENKO VALERIJ SEMENOVICH;SGIBNEV ANDREJ VIKTOROVICH;KHUSNUTDINOVA LILIJA MIDEKHATEVNA
分类号 G01N33/48;C12N1/02 主分类号 G01N33/48
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