发明名称 Pyrazole-amine compounds for the treatment of neurodegenerative disorders
摘要 The present invention relates to compounds of the Formula wherein R1, R3, R4, R5, R6, R7 and R8 are as defined. Compounds of the Formula I have activity inhibiting production of Abeta-peptide. The invention also relates to pharmaceutical compositions and methods of treating disorders and diseases, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
申请公布号 US7468386(B2) 申请公布日期 2008.12.23
申请号 US20070773831 申请日期 2007.07.05
申请人 PFIZER INC. 发明人 CHEN YUHPYNG L.;ZHANG LEI
分类号 A61K31/415;A61K31/4155;A61K31/416;C07D231/16;C07D231/40;C07D405/12 主分类号 A61K31/415
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