发明名称 |
Protein S functional assay |
摘要 |
The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant tissue factor (pTF or rTF), purified natural or synthetic phospholipid (pPL or sPL) and activated protein C (APC) or protein C activator (PCA). The clotting time is then measured and compared to a standard curve or a normal control.
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申请公布号 |
US7468257(B2) |
申请公布日期 |
2008.12.23 |
申请号 |
US20040013121 |
申请日期 |
2004.12.15 |
申请人 |
INSTRUMENTATION LABORATORY CORPORATION |
发明人 |
DAI YONG;YE BIQING;CHEN KUI;BRUGUERA PAU;LAWSON DANIEL E;TANG SHAMAY |
分类号 |
C12Q1/37;C07K14/745;G01N33/86 |
主分类号 |
C12Q1/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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