发明名称 |
Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
摘要 |
This invention provides novel arylindenopyridines and arylindenopyrimidines of the formula: wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
|
申请公布号 |
US7468373(B2) |
申请公布日期 |
2008.12.23 |
申请号 |
US20050170484 |
申请日期 |
2005.06.29 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
HEINTZELMAN GEOFFREY R.;BULLINGTON JAMES LAWRENCE;RUPERT KENNETH C. |
分类号 |
A61K31/505;A61K31/473;A61K31/4741;A61K31/519;C07D221/16;C07D239/00;C07D401/04;C07D401/12;C07D405/04;C07D409/04;C07D491/02;C07D491/04 |
主分类号 |
A61K31/505 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|