| 发明名称 |
ALMOND ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITOR |
| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: described is novel compound Ph(3-Cl)(5-OCHF2)-(R)CH(OH)C(O)-(S)Aze-Pab(2,6-diF)(OH) of formula: or its pharmaceutically acceptable salt. ^ EFFECT: using compound as active ingredient for preparation of medicine for treatment of condition, which demands inhibiting of trombone. ^ 12 cl, 7 ex |
| 申请公布号 |
RU2341516(C2) |
申请公布日期 |
2008.12.20 |
| 申请号 |
RU20040103625 |
申请日期 |
2002.08.30 |
| 申请人 |
ASTRAZENEKA AB |
发明人 |
INGKHARDT TOR;JOKHANSSON ANDERS;SVENSSON ARNE |
| 分类号 |
C07D205/04;A61K31/397;A61P7/02;C07C45/00;C07C45/29;C07C45/51;C07C45/67;C07C45/71;C07C47/575;C07C59/56;C07C59/64;C07C69/732;C07C69/734;C07C69/738;C07C205/59;C07D207/16;C07D213/34;C07D213/54;C07D239/28;C07D261/08;C07D401/12;C07D403/12;C07D413/12 |
主分类号 |
C07D205/04 |
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