发明名称 3- (4-{ [4- (4-{ [3-(3, 3-Dimethyl-1-Piperidinyl) Propyl] Oxy} Phenyl) -1-Piperidinyl] Carbonyl}-1-Naphthalenyl) Propanoic or Propenoic Acid as H1 and H3 Receptor Antagonists for the Treatment of Inflammatory and/or Allergic Disorders
摘要 The present invention relates to a compound of formula (I), or a salt thereof wherein the naphthalene ring is substituted in the 2, 3, 4, 5, 6, 7 or 8 position by R1, and R1 represents -CH2CH2COOH or -CH-C(CH3)COOH, and to processes for their preparation, to compositions containing them and to their use in the treatment of various inflammatory and/or allergic diseases, such as diseases such as allergic rhinitis.
申请公布号 US2008312280(A1) 申请公布日期 2008.12.18
申请号 US20060158185 申请日期 2006.12.19
申请人 HODGSON SIMON TEANBY;PROCOPIOU PANAYIOTIS ALEXANDROU;VINADER BRUGAROLAS MARIA VICTORIA 发明人 HODGSON SIMON TEANBY;PROCOPIOU PANAYIOTIS ALEXANDROU;VINADER BRUGAROLAS MARIA VICTORIA
分类号 A61K31/4545;C07D401/12 主分类号 A61K31/4545
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