发明名称 |
Enteric-Coated Glucosinolates And Beta-Thioglucosidases |
摘要 |
The present invention relates to a particulate composition comprising enteric-coated glucosinolate and beta-thioglucosidase particles. The present invention further provides a method of converting glucosinolate to isothiocyanate in the small intestine comprising orally administering to a subject an enteric-coated chemoprotectant precursor composition comprising enteric-coated glucosinolate and beta-thioglucosinodase particles. In another aspect, uncoated glucosinolate and beta-thioglucosinodase particles may be provided in an enteric-coated capsule. Preferably, the glucosinolate is glucoraphanin and the beta-thioglucosidase is myrosinase. The enteric coating targets the compound for release in the small intestine where beta-thioglucosinodase enzyme converts glucosinolate to chemoprotectant isothiocyanate.
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申请公布号 |
US2008311192(A1) |
申请公布日期 |
2008.12.18 |
申请号 |
US20070761843 |
申请日期 |
2007.06.12 |
申请人 |
KRAFT FOODS HOLDINGS, INC. |
发明人 |
WEST LESLIE GEORGE;WINDSOR NICOLE LEE;GAONKAR ANILKUMAR GANAPATI;MATUSHESKI NATHAN V.;KIM NAM-CHEOL;LUDWIG CATHY JEAN;LAWRENCE LESLIE LEWIS |
分类号 |
A61K9/14;A61K9/48;A61K38/47 |
主分类号 |
A61K9/14 |
代理机构 |
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主权项 |
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地址 |
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