发明名称 7-ARYL-3, 9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES
摘要 The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
申请公布号 US2008312242(A1) 申请公布日期 2008.12.18
申请号 US20080168666 申请日期 2008.07.07
申请人 ACTELION PHARMACEUTICALS, LTD. 发明人 BEZENCON OLIVIER;BUR DANIEL;FISCHLI WALTER;REMEN LUBOS;RICHARD-BILDSTEIN SYLVIA;WEBER HANS-PETER;WELLER THOMAS
分类号 A61K31/4995;C07D471/08;A61K45/06;A61P3/10;A61P9/10;A61P9/12;A61P13/12;A61P15/10;A61P27/06;A61P37/02;C07D 主分类号 A61K31/4995
代理机构 代理人
主权项
地址