| 摘要 |
<p>Disclosed is a method for producing an extended release tablet, which enables to efficiently produce such an extended release tablet having excellent slow release property that is suppressed in initial release of a drug but capable of completing release of the drug after a predetermined time. Specifically disclosed is a method for producing an extended release tablet wherein a mixture, which is composed of a hydroxyalkyl cellulose (A) whose 2% by mass aqueous solution has a viscosity at 20‹C of 1-50 mPaÀs, a hydroxyalkyl cellulose (B) whose 2% by mass aqueous solution has a viscosity at 20‹C of not less than 100 mPaÀs, an active ingredient and an additive, is granulated by dry granulation and then the thus-obtained granules are formed into tablets, or alternatively the mixture is directly formed into tablets. ® KIPO & WIPO 2009</p> |
