发明名称 NOVEL PROCESSES TO FORM-I OF OLANZAPINE
摘要 <p>A process for obtaining crystalline Form-I olanzapine comprising the following: a) dissolving crude olanzapine in a solvent to form a solution, b) optionally drying by azeotropic distillation to remove water, c) precipitating by adding the solution of step (a) to an antisolvent, and d) isolating the precipitated crystalline Form-I olanzapine by filtration and drying at ambient temperature.</p>
申请公布号 WO2008151430(A1) 申请公布日期 2008.12.18
申请号 WO2008CA01124 申请日期 2008.06.12
申请人 APOTEX PHARMACHEM INC.;CHE, DAQING;KOTHAKONDA, KIRAN KUMAR;MCPHAIL, CAMERON;GUNTOORI, BHASKAR REDDY 发明人 CHE, DAQING;KOTHAKONDA, KIRAN KUMAR;MCPHAIL, CAMERON;GUNTOORI, BHASKAR REDDY
分类号 C07D495/04 主分类号 C07D495/04
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