| 摘要 |
The present invention describes optical discs on which polymer molecules can be analysed. There is a method for determining a plurality of characteristics of a target molecule, said target being localised on an optical substrate comprising pits and lands, comprising the steps of: (i) carrying out a series of reactions to interrogate different defined characteristics of the target molecule, wherein each of said reactions occurs in a distinct pit; (ii) treating the optical substrate to modify either those pits where a reaction has occurred, or alternatively, those pits where a reaction has not occurred, to alter the reflective characteristics of the pits; and (iii) measuring reflectivity within the pits, to thereby determine different characteristics of the target.
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