发明名称 HEPATOCELLULAR CARCINOMA-RELATED GENE AND POLYPEPTIDE, AND METHOD FOR DETECTING HEPATOCELLULAR CARCINOMA
摘要 <P>PROBLEM TO BE SOLVED: To provide a gene which rises in expression in hepatocellular carcinoma, to provide a polypeptide encoded by the gene, and a method for detecting hepatocellular carcinoma. <P>SOLUTION: DDEFL1, VANGL1, a LGN gene, and a polypeptide encoded by each of these genes, an expression vector, and a transformant are provided, respectively. The method for detecting hepatocellular carcinoma using a probe including each of these gene arrangements, a primer, and an antibody to each of the polypeptides, is also provided. Besides, an antisense nucleotide sequence of each of these genes is provided, which can be used to inhibit the growth of hepatocellular carcinoma. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2008301816(A) 申请公布日期 2008.12.18
申请号 JP20080131279 申请日期 2008.05.19
申请人 ONCOTHERAPY SCIENCE LTD 发明人 NAKAMURA YUSUKE;FURUKAWA YOICHI
分类号 C12N15/09;G01N33/566;A61K31/7088;A61K31/711;A61P1/16;A61P35/00;C07H21/04;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/64;C12N15/12;C12P21/02;C12Q1/02;C12Q1/68;G01N33/574 主分类号 C12N15/09
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