发明名称 |
METHOD FOR DETERMINING ENANTIOMERIC PURITY OF DARIFENACIN AND INTERMEDIATES |
摘要 |
The present invention relates to a method for differentiating and quantifying the enantiomers, thereby determining the enantiomeric purity, of darifenacin and its intermediate compounds and salts thereof. In addition, the invention relates to a method for differentiating and quantifying the enantiomers, thereby determining the enantiomeric purity of compounds of formula (I): wherein Y is hydrogen or a substituent of the formula (II): including the differentiation and quantification of compounds of formula (I) of varying enantiomeric purity from their corresponding enantiomers. The invention further relates to a process for preparing enantiomerically pure darifenacin using enantiomerically pure starting compounds which have been previously differentiated and quantified according to the method of the invention.
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申请公布号 |
CA2691239(A1) |
申请公布日期 |
2008.12.18 |
申请号 |
CA20082691239 |
申请日期 |
2008.06.13 |
申请人 |
MEDICHEM, S.A. |
发明人 |
SOLDEVILLA MADRID, NURIA;BOSCH I LLADO, JORDI |
分类号 |
C07D405/06;B01J20/285;C07B57/00;C07D207/04;G01N30/02 |
主分类号 |
C07D405/06 |
代理机构 |
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