发明名称 Bicyclic Piperazines as Metabotropic Glutatmate Receptor Antagonists
摘要 The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where Ar1, A, Hy, R1, m and n are as defined in the description. The invention also includes pharmaceutical compositions and uses of, and processes of making the compounds, as well as methods of medical treatment of mGluR5-mediated disorders.
申请公布号 US2008312240(A1) 申请公布日期 2008.12.18
申请号 US20060997541 申请日期 2006.08.04
申请人 ASTRAZENECA AB 发明人 EDWARDS LOUISE;ISAAC METHVIN;SLASSI ABDELMALIK;SUN GUANG-RI;XIN TAO;MINIDIS ALEXANDER;DOVE PETER
分类号 A61K31/4985;A61P1/00;A61P25/00;C07D401/14;C07D403/14;C07D413/14;C07D471/04 主分类号 A61K31/4985
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