摘要 |
<p>1505461 Esters of corticoids with a substituted acetic acid AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO ACRAF SpA 9 Jan 1976 [13 Feb 1975] 00873/76 Headings C2U and C2C Novel steroids of the formula (wherein R 2 is #-OH or O and there is an opional #<SP>1</SP>-double bond) are prepared by esterification of cortisone, hydrocortisone, prednisone or prednisolone with [(1-benzyl-1H-indazol-3- yl)oxy] acetic acid chloride, which is prepared from the parent acid and thionyl chloride. They are anti-inflammatory agents and may be made up into pharmaceutical compositions with suitable carriers.</p> |