| 摘要 |
The present invention relates to certain novel pyran analogs of 4,5,13,14-tetradehydro-PGI1 compounds wherein the C-5 to C-6 double bond of prostacyclin (PGI2) is isomerized to the C-4 to C-5 position, the heterocyclic ring of PGI2 is enlarged to 5 carbon atoms, and the C-13 to C-14 double bond is further unsaturated to a triple bond. These novel pyran analogs are useful as smooth muscle stimulators.
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