发明名称 IMMUNOSUPPRESSING AGENT
摘要 PURPOSE:To provide an immunosuppressing agent containing cholecalciferol or its derivative as an effective component, and effective to the immunological hyperergasia such as chronic thyroaderitis, autoimmune hemolytic anemia, etc. CONSTITUTION:An agent containing as an effective component, known cholecalciferol or its derivative (e.g. 1alpha-hydroxycholecalciferol) found in tuna-liver oil or synthesized by the UV-irradiation of 7-dehydrocholesterin. It has been found that the compound is effective not only to control the calcium metabolism but also to suppress the immunity of the body. The necessary dose is very small, and the blood concentration of 0.01mg/ml-1mug/ml is sufficient. It is preferable to be administered as a soft capsule. The agent has improved effectiveness and reduced side effects.
申请公布号 JPS5626820(A) 申请公布日期 1981.03.16
申请号 JP19790101211 申请日期 1979.08.10
申请人 CHUGAI PHARMACEUTICAL CO LTD 发明人 AOKI TADAO;MIYAKOSHI HIDEO;HIRASAWA YOSHIHEI;NISHII YASUHO
分类号 A61K31/59;A61P37/00;A61P37/06 主分类号 A61K31/59
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