| 摘要 |
A new class of alkylthiophenoxyalkylamine derivatives and methods for preparation are described. The compounds have vasodilating and antispasmodic activity, inhibit blood platelet aggregation and are substantially free of beta-adrenergic blocking effects. They are particularly valuable in the treatment of disease states responsive to vasodilation such as obstructive peripheral vascular diseases and cerebral vascular deficiencies. Representative and preferred embodiments of the invention are N-[3-[4-(methylthio)phenoxy]propyl]octylamine and N-[3-[4-(1-methylethyl)thio]phenoxy]-propyl]octylamine. |
