N-Formyl leurosine derivatives in a dosage form effective for treating lymphoid leukemia

摘要

New leurosine derivatives of the general formula (1), <IMAGE> (I) wherein R stands for hydrogen or formyl, or pharmaceutically acceptable acid addition salts thereof were prepared by oxidizing leurosine or an acid addition salt thereof, optionally formylating the thus-obtained product and then separating, and, if desired, converting any of the free bases into its acid addition salt.