发明名称 |
PURIFICATION OF S-SULFONATED GAMMAGLOBULIN ONION-EXCHANGE RESINS |
摘要 |
Process for the production of a highly purified S-sulfonated gammaglobulin by treating an S-sulfonated gammaglobulin obtained by sulfonating a conventional gammaglobulin with an ion exchanger in a buffer solution for development, and thereby absorbing single molecular S-sulfonated gammaglobulin thereto, and eluting the single molecular S-sulfonated gammaglobulin with a buffer solution for elution. This process can give the desired S-sulfonated gammaglobulin having a high content of single molecule and an extremely small anticomplementary activity (e.g. CH50 of 10% or less) and also an excellent shaking stability from the conventional gammaglobulin in an industrial scale. |
申请公布号 |
GB2039490(B) |
申请公布日期 |
1983.02.16 |
申请号 |
GB19800001629 |
申请日期 |
1980.01.17 |
申请人 |
CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
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分类号 |
A61K39/395;C07K16/06;(IPC1-7):07G7/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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