Cyclic compounds and their use

摘要

Compounds of the formula (I): (I) and pharmaceutically acceptable salts and pro-drugs thereof, wherein: Ar is a phenyl group optionally substituted by one or two moieties selected from halogen, C1-4 alkyl, methoxy, methylthio or trifluoromethyl, or a 2-thienyl group or N-methyl-2-pyrryl group optionally substituted by one or two C1-4 alkyl groups; R is hydrogen or methyl; and n is 0 or 1 having useful anti-inflammatory and/or analgesic activity, pharmaceutical compositions containing them, and processes for their preparation.