发明名称 Tetrapeptide derivatives
摘要 <p>L - Tryptophanyl - L - methionyl - L-aspartyl-L-phenylalanine amide and its acid addition salts is prepared by removing the protecting groups from the corresponding N-protected tetrapeptamide ester. t - Butoxycarbonyl - L - tryptophanyl - L-methionyl - (b - t - butyl) - L - aspartyl - L-phenylalanine amide, L-methionyl-(b -t-butyl)-L-aspartyl - L - phenylalanine amide, N - (o - nitro-phenylsulphenyl) - L - methionyl - (b - t - butyl)-L - aspartyl - L - phenylalanine amide, (b - t-butyl) - L - aspartyl - L - phenylalanine amide, N - benzyloxycarbonyl - (b - t - butyl) - L - aspartyl - L - phenylalanine amide and Na - (t-butyloxycarbonyl) - L - tryptophan - 2,4,5-trichlorophenyl and p-nitrophenyl esters are prepared as starting materials. Reference has been directed by the Comptroller to Specification 878,732.</p>
申请公布号 GB1042484(A) 申请公布日期 1966.09.14
申请号 GB19640026352 申请日期 1964.06.25
申请人 IMPERIAL CHEMICAL INDUSTRIES LIMITED 发明人 HARDY PAUL MARTIN;KENNER GEORGE WALLACE;SHEPPARD ROBERT CHARLES;MORLEY JOHN SELWYN
分类号 C07K5/117 主分类号 C07K5/117
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