摘要 |
Piperazine and homopiperazine compounds of the formula: <IMAGE> in which: A is a hydrocarbon radical from C3 to C5, in a straight or branched chain, which may contain one or two double bonds, and optionally substituted by one or more OH; B is CH or a nitrogen atom; m is 2 or 3; X-Y- represents -CH=CH- (CR'R'')n- in which n is zero or 1, and R' and R'' are hydrogen or methyl; Z is oxygen or sulfur, R is hydrogen, alkyl from C1 to C5, cycloalkyl from C3 to C7, or phenyl optionally substituted by fluorine, chlorine or alkyl from C1 to C5, and T is hydrogen, fluorine, chlorine or alkyl from C1 to C5. These compounds and physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of all kinds of tissular hypoxy.
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