发明名称 |
PROCEDE POUR LA PREPARATION DES LACTAMES |
摘要 |
.beta.-Lactams having a sulfonic acid substituent in the 1-position and an amine function in the 3-position and having the formula: (see fig. I) wherein R1 is H or acyl derived from a carboxylic acid; R2 is H or alkoxy; R3 and R4, the same or different, are H, alkyl, cycloalkyl, phenyl or substituted phenyl, or one of R3 and R4 is H and the other is alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl; and X is H or SO3X is SO3-M+ wherein M+ is a cation, and the use of said .beta.-lactams as antibiotics. |
申请公布号 |
RO86528(A) |
申请公布日期 |
1985.03.15 |
申请号 |
RO19810111297 |
申请日期 |
1981.02.06 |
申请人 |
ER SQUIBB AND SONS INC,US |
发明人 |
SYKES RICHARD B.,US;PARKER WILLIAM L.,US;CIMARUSTI CHRISTOPHER M.,US;KOSTER WILLIAM H.,US;SLUSARCHYK WILLIAM A.,US;FRITZ ALAN W.,US;FLOYD DAVID M.,US |
分类号 |
C07D205/08;A61K31/40;C07D201/02;C07D205/085;C07D401/00;C07D417/06;C07D471/04;C07F7/08;C07F7/10;C07F9/6558;C12P17/10 |
主分类号 |
C07D205/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|