发明名称 1-HETERO-6-(1-HYDROXYETHYL)-2-SR8-1- CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACID
摘要 Disclosed are 1-hetero-6-[1-hydroxyethyl]-2-SR<8>-1-carbadethiapen-2-em-3-COOR<4> compounds having the structure: <CHEM> wherein R<4> is, e.g., hydrogen, R<8> is, e.g., alkyl and R<9> is, e.g., halogen; the pharmaceutically acceptable salt and ester derivatives thereof and use as antibiotics. Also disclosed are processes for the preparation of such compounds and pharmaceutical compositions comprising such compounds.
申请公布号 JPS60233077(A) 申请公布日期 1985.11.19
申请号 JP19850085609 申请日期 1985.04.23
申请人 MERCK & CO INC 发明人 ROBUJI DEE KAMA;BAATON JII KURISUTENSEN;DEIBUITSUDO ETSUCHI SHIII
分类号 C07D477/00;A61K31/397;A61K31/40;A61P31/04;C07D205/08;C07D207/12;C07D211/46;C07D211/54;C07D279/12;C07D295/205;C07D477/26;C07D519/00;C07F7/18;C07F9/6561 主分类号 C07D477/00
代理机构 代理人
主权项
地址