发明名称 REMEDY FOR ULCERATIVE COLITIS
摘要 PURPOSE:To obtain a remedy for ulcerative colitis completely eliminating main symptoms such as diarrhea in active state, bloody excrement, tormina, etc., in a short period, facilitating introduction to remission period, containing human blood coagulation factor XIII as an active ingredient. CONSTITUTION:Human blood coagulation factor XIII widely existing in plasma or placenta, etc., as an active ingredient is pharmaceutically manufactured by a conventional procedure to give the aimed substance. Administration by injection is preferable, parenteral administration by microcapsulation or embedding method, oral administration with solution, tablet, capsule agent can be performed and suppository can be administered. A dose is <=5,000 units daily, preferably 1,500-3,000 units and administered for 3-5 days. Human blood coagulation factor XIII preparations have been practically used as a remedy for wound remedy disorder, etc., has not fear of side effects and toxicity.
申请公布号 JPS63196520(A) 申请公布日期 1988.08.15
申请号 JP19870026387 申请日期 1987.02.09
申请人 HOECHST JAPAN KK 发明人 URABE MIKIO;TANAKA SATOSHI;TSUMURA KENICHIRO
分类号 A61K35/14;A61K35/16;A61K35/50;A61K38/00;A61K38/43;A61P1/04;C12N9/10 主分类号 A61K35/14
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