发明名称 |
Inhibition of HTLV-III by exogenous oligonucleotides |
摘要 |
Inhibition of HTLV-III by adminstration of an oligonucleotide complementary to highly conserved regions of the HTLV-III genome necessary for HTLV-III replication and/or gene expression is described, as are oligodeoxynucleotide sequences which are complementary to those regions, methods of inhibiting HTLV-III replication and gene expression and methods of determining the presence or absence of HTLV-III virus in samples such as blood, saliva, urine and tears.
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申请公布号 |
US4806463(A) |
申请公布日期 |
1989.02.21 |
申请号 |
US19860867231 |
申请日期 |
1986.05.23 |
申请人 |
WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY |
发明人 |
GOODCHILD, JOHN;ZAMECNIK, PAUL C. |
分类号 |
C07H21/00;C12N15/113;C12Q1/70;G01N33/569;(IPC1-7):C12Q1/70;C12Q1/02;A61K39/12 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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