发明名称 AMINO ACID DERIVATIVES
摘要 The compounds of the formula …<IMAGE>… in which A, R<1>, R<2>, R<3> and R<4> have the meaning stated in Claim 1,… in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates, and pharmaceutically utilisable salts thereof, inhibit the action of the natural enzyme renin and can accordingly be used in the form of pharmaceutical products for controlling or preventing high blood pressure and heart failure. They can be prepared by various processes known per se.
申请公布号 ZA9002185(B) 申请公布日期 1990.12.28
申请号 ZA19900002185 申请日期 1990.03.21
申请人 F HOFFMANN-LA ROCHE A.G. 发明人 QUIRICO BRANCA;HANS PETER MAERKI;WERNER NEIDHART;HENRI RAMUZ;WOLFGANG WOSTL
分类号 A61K31/16;A61K31/27;A61K31/38;A61K31/381;A61K31/415;A61K31/425;A61K31/426;A61K31/4427;A61K31/445;A61K38/00;A61K38/55;A61P9/00;A61P9/12;C07C237/06;C07C271/16;C07C271/18;C07C271/20;C07D231/12;C07D233/54;C07D233/64;C07D277/20;C07D277/30;C07D333/24;C07D401/12;C07D403/12;C07K5/02;C07K5/065 主分类号 A61K31/16
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