| 发明名称 |
THE CLASS II PROTEIN OF THE OUTER MEMBRANE OF NEISSERIA MENINGITIDIS HAVING IMMUNOLOGIC CARRIER AND ENHANCEMENT PROPERTIES |
| 摘要 |
34/JWW14 35/JWW15 18160IA TITLE OF THE INVENTION THE CLASS II PROTEIN OF THE OUTER MEMBRANE OF NEISSERIA MENINGITIDIS HAVING IMMUNOLOGIC CARRIER AND ENHANCEMENT PROPERTIES The Class II major immuno-enhancing protein (MIEP) of Neisseria meningitidis, purified directly from the outer membrane of Neisseria meningitidis, or obtained through recombinant cloning and expression of DNA encoding the MIEP of Neisseria meningitidis, has immunologic carrier as well as immunologic enhancement, cytokine-inducing (such as interleukin-2 (I1-2)) and mitogenic properties. |
| 申请公布号 |
AU8114091(A) |
申请公布日期 |
1992.01.23 |
| 申请号 |
AU19910081140 |
申请日期 |
1991.07.18 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ALLEN I. OLIFF;MARGARET A LIU;ARTHUR FRIEDMAN;JOSEPH Y TAI;JOHN J DONNELLY |
| 分类号 |
A61K38/00;A61K;A61K39/00;A61K39/02;A61K39/095;A61K39/12;A61K39/35;A61K39/385;A61K39/39;A61P37/04;A61P43/00;C07K;C07K14/005;C07K14/195;C07K14/41;C07K14/705;C07K19/00;C12N1/20;C12N15/09;C12N15/31;C12P21/00;C12R1/19;C12R1/36;C12R1/865 |
主分类号 |
A61K38/00 |
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