发明名称 |
DNA CAPABLE OF SITE-SPECIFIC INTEGRATION INTO MYCOBACTERIA |
摘要 |
A DNA for integrating DNA into a mycobacterium chromosome portion which includes a first DNA sequence which is a phage DNA portion encoding bacteriophage integration into a mycobacterium chromosome, and a second DNA sequence encoding a protein or polypeptide heterologous to the mycobacterium in which the DNA is to be integrated. Such DNA may be integrated into mycobacteria, which may then be administered as a vaccine and/or therapeutic agent. |
申请公布号 |
WO9201783(A1) |
申请公布日期 |
1992.02.06 |
申请号 |
WO1991US04833 |
申请日期 |
1991.07.09 |
申请人 |
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNI;UNIVERSITY OF PITTSBURGH |
发明人 |
JACOBS, WILLIAM, R.;HATFULL, GRAHAM |
分类号 |
A61K39/04;A61K38/00;A61K39/00;A61P31/04;C07K14/16;C12N1/21;C12N15/09;C12N15/74;C12N15/90;C12P21/02;C12R1/32 |
主分类号 |
A61K39/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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