ANTI-HYPERTENSIVE TETRALINS

摘要

The present invention is concerned with compounds of formula (I), wherein R1 is hydrogen, hydroxy, C1-4 alkyl, halo (e.g., chloro), carbamoyl, aminosulfonyl, C1-4 alkylsulfonylamino or C1-4 alkyl(C1-4 alkylsulfonyl)amino; R2 is hydrogen, hydroxy, halo (e.g., chloro), C1-4 alkoxycarbonyl, aminosulfonyl or C1-4 alkylsulfonylamino; R3 is hydrogen, hydroxy or C1-4 alkoxy; R4 is hydrogen, C1-4 alkoxy, halo (e.g., chloro or bromo) or nitro and pharmaceutically acceptable salts thereof provided that R1 and R2 are not both hydrogen and that when R1 is methylsulfonylamino and R4 is hydrogen, R3 is not hydrogen or C1-4 alkoxy, with processes for preparing same and with their use in medicine for the treatment of hypertension.