MONOCLONAL ANTIBODY FOR USE IN DIAGNOSING ALZHEIMER'S DISEASE, HYBRIDOMA SECRETING SAID ANTIBODY AND PREPARATION METHOD THEREFOR

摘要

A monoclonal antibody directed against part of the extracellular domain of the APP precursor of peptide A beta P is provided for recognising both kinds of lesions which are typical of Alzheimer's disease as well as the soluble form of the APP precursor. The use of this antibody for detecting said lesions and for assaying said soluble form of APP, as well as the hybridoma which produces said monoclonal antibody, a method for preparing said hybridoma, and a protein used as an antigen in said method, are also described.