发明名称 bibNUCLIDINE DERIVATIVES
摘要 Compounds of formula (I), wherein R<1> is methoxy and R<2> is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl; and the pharmaceutically acceptable salts of such compounds. These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.
申请公布号 WO9221677(A1) 申请公布日期 1992.12.10
申请号 WO1992US03317 申请日期 1992.04.28
申请人 PFIZER INC. 发明人 ITO, FUMITAKA;KONDO, HIROSHI;SHIMADA, KAORU;NAKANE, MASAMI;LOWE, JOHN, ADAMS, III;ROSEN, TERRY, JAY;YANG, BINGWEI, VERA
分类号 C07D453/02;A01N43/90;A61K;A61K31/395;A61K31/435;A61K31/439;A61K31/44;A61K31/445;A61P1/00;A61P1/16;A61P11/00;A61P25/00;A61P25/04;A61P25/20;A61P25/24;A61P29/00;A61P43/00;C07D;C07D453/00;C07D453/04;C07D471/10 主分类号 C07D453/02
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