发明名称 |
BILOBALIDE DERIVATIVES, THEIR APPLICATIONS AND FORMULATIONS CONTAINING THEM |
摘要 |
Complexes between natural or synthetic phospholipids and bilobalide, a sesquiterpene extracted from the leaves of Gingko biloba, are disclosed, as well as the preparation thereof and their therapeutic application as antiinflammatory agents and as agents for the treatment of disorders associated with inflammatory or traumatic neuritic processes. These new compounds, which exhibit a different bioavailability compared with free bilobalide, are suitable for incorporation into pharmaceutical formulations for systemic and topical administration: the latter route has been found to be particularly useful for the treatment of common peripheral disorders associated with inflammatory or neurodystrophic alterations.
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申请公布号 |
US5202313(A) |
申请公布日期 |
1993.04.13 |
申请号 |
US19910651598 |
申请日期 |
1991.02.06 |
申请人 |
INDENA S.P.A. |
发明人 |
BOMBARDELLI, EZIO;MUSTICH, GIUSEPPE |
分类号 |
A61K8/55;A61K8/00;A61K8/04;A61K8/58;A61K8/96;A61K9/127;A61K31/366;A61K31/685;A61P17/00;A61P25/02;A61P29/00;A61Q19/00;C07D493/14;C07D493/20;C07F9/10 |
主分类号 |
A61K8/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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