| 发明名称 |
METHODS AND COMPOSITIONS FOR TARGETING THE VASCULATURE OF SOLID TUMORS |
| 摘要 |
The present invention relates generally to methods and compositions for targeting the vasculature of solid tumors using immunologically-based reagents. In particular aspects, antibodies carrying diagnostic or therapeutic agents are targeted to the vasculature of solid tumor masses through recognition of tumor vasculature-associated antigens, or through the specific induction of endothelial cell surface antigens on vascular endothelial cells in solid tumors.
|
| 申请公布号 |
CA2452130(A1) |
申请公布日期 |
1993.09.16 |
| 申请号 |
CA19932452130 |
申请日期 |
1993.03.05 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS |
发明人 |
BURROWS, FRANCIS J.;THORPE, PHILIP E. |
| 分类号 |
A61K38/00;A61K39/00;A61K45/00;A61K47/42;A61K47/48;A61K49/00;A61K49/08;A61K49/16;A61K51/10;A61P35/00;C07K16/22;C07K16/28;C07K16/30;C12P21/08;(IPC1-7):A61K47/48 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
