| 摘要 |
FIELD: technological processes; pharmacology. ^ SUBSTANCE: method is implemented in the following manner: pH of initial solution is brought to 4.6-4.95, and caprilat- and/or heptanoate-ions are added to it, while pH is maintained at the level of 4.8-4.95. Supernatant solution is incubated under conditions, at which concentration of caprilat- and/or heptanoate-ions makes 10-30 mM. Filtered solution is applied on anion-exchanging resin, under conditions that provide binding of contaminating admixtures with resin in the absence of considerable binding of antibodies with resin. ^ EFFECT: method makes it possible to produce preparation of antibody that is purified, virologically safe and inactivated from virological point of view. ^ 22 cl, 2 dwg, 2 tbl, 3 ex |
