发明名称 METHOD OF PRODUCING OF L-LYSINE OR L-THREONINE BY MEANS OF BACTERIA ESCHERICHIA HAVING ATTENUATED ACTIVITY OF MALEIC ENZYME
摘要 FIELD: medicine. ^ SUBSTANCE: method of producing of L-lysine or L-threonine includes plating of bacteria in a medium for producing and secretion of L-lysine or L-threonine, collecting and allocation of L-lysine or L-threonine from the medium. Thus the specified bacterium represents bacterium Escherichia which possesses ability to produce a L-lysine or L-threonine, and where the specified bacterium is modified so that normal function of maleic enzyme in a cell is broken and where maleic enzyme is coded by the sfcA gene and/or the b2463 gene. ^ EFFECT: high degree of efficiency. ^ 12 cl, 4 dwg, 11 tbl, 6 ex
申请公布号 RU2337140(C2) 申请公布日期 2008.10.27
申请号 RU20060101328 申请日期 2004.07.29
申请人 ADZINOMOTO KO., INK. 发明人 VAN DIN STEFEN;IVATANI SINTARO;USUDA JOSIKHIRO;MATSUI KAZUKHIKO;NAKAI JUTA;SUZUKI TOMOKO;MORIJA MIKA;TSUDZI JUITIRO;UEDA TAKUDZI
分类号 C12N15/09;C12P13/08;C12N1/00;C12N1/21;C12N9/04;C12P1/00;C12Q1/00;C12R1/185 主分类号 C12N15/09
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