| 摘要 |
FIELD: medicine; pharmacology. ^ SUBSTANCE: present group of inventions is referred to biologically active compounds characterised by the formula (I), their pharmaceutically acceptable salts, solvates and stereoisomers, the pharmaceutical compositions containing specified compounds, method of obtaining, the intermediate compounds used for obtaining of compounds of the formula (I), and methods of treatment of the painful conditions mediated by muscarine receptors with use of specified compounds where R4 represents hydrogen; R5 is chosen from C1-6alkyl, C3-6cycloalkyl and -CH2-R8; where the alkyle group is unessentially replaced by or 1-5 fluorine-substituents; R8 is chosen from C3-6cycloalkyl or phenyl; a, b and with are 0; d is 1; e is 8 or 9. ^ EFFECT: obtaining of new biologically active compounds for treatment of some diseases. ^ 10 cl, 27 ex, 15 tbl |
