发明名称 |
PURIFIED PEPTIDES AND COMPOUNDS CONTAINING THEREOF |
摘要 |
The invention is based on peptides and peptide-targeted multimeric contrast agents, wherein a single peptide can function both as a targeting group and a point of attachment for one or more chelates at both the N and C-termini, either directly or via an optional intervening linker. Contrast agents of the invention maintain binding affinity for biological targets such as fibrin. |
申请公布号 |
UA84432(C2) |
申请公布日期 |
2008.10.27 |
申请号 |
UA20060001920 |
申请日期 |
2002.07.30 |
申请人 |
EPIX MEDICAL, INC. |
发明人 |
ZHANG ZHAODA;CARAVAN PETER D.;MCMURRY THOMAS J.;KOLODZIEJ ANDREW;NAIR SHRIKUMAR;AMEDIO JOHN C.;DUMAS STEPHANE;WANG XIFANG;SUN WEI-CHUAN;NIVOROZHKIN ALEXANDER L.;KOERNER STEFFI K. |
分类号 |
A61B5/055;A61K49/00;A61K47/48;A61K49/08;C07K5/117;C07K7/06;C07K7/08 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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