| 发明名称 |
AGENTS FOR PROPHYLAXIS OR TREATMENT OF NEUROLOGICAL RELATED DISEASES AND CONDITIONS |
| 摘要 |
Mimetics of a region of DynI including the serine residues S774 and S778 o r phosphorylatable amino acids in homologous positions are provided. The mimetics exclude or do not imitating at least one phosphorylation site provided by th e serine residues or phosphorylatable amino acids. The mimetics have application in t he prophylaxis or treatment of neurological diseases or conditions. The mimetic s can also be used to inhibit synaptic transmission.
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| 申请公布号 |
CA2585247(A1) |
申请公布日期 |
2008.10.27 |
| 申请号 |
CA20072585247 |
申请日期 |
2007.04.30 |
| 申请人 |
THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED;CHILDREN'S MEDICAL RESEARCH INSTITUTE;THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH |
发明人 |
ROBINSON, PHILLIP J.;COUSIN, MICHAEL A.;MCCLUSKEY, ADAM |
| 分类号 |
C12N9/14;A61K38/02;A61K38/10;A61K38/46;A61K45/06;A61P25/00;C07K7/08;G01N33/53 |
主分类号 |
C12N9/14 |
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