| 摘要 |
FIELD: medicine; pharmacology. ^ SUBSTANCE: polypeptides under the invention include amino-acid sequence, structurally related sequence SEQ ID NO:1 resulted in the text of the description, to use of such polypeptides as immunogens, including as a part of compositions. The invention opens also expression systems for producing such polypeptides. The sequence SEQ ID NO:1 represents a truncated derivative of full-size polypeptide S. aureus. This full-size polypeptide is designated in the invention as full-size "ORF0657n". It is established, that the polypeptides described in the invention and containing amino-acid sequence are SEQ ID NO:1. ^ EFFECT: polypeptides cause protective immune response against staphylococcus aureus. ^ 43 cl, 56 dwg, 4 tbl, 17 ex
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