发明名称 |
Targeted ubiquitination of proteins and screening methods using a new class of ubiquitin ligase proteins |
摘要 |
Members of the IpaH superfamily constitute a novel class of E3 ubiquitin ligases which are useful for engineering products which modulate trafficking and destruction of target proteins inside a cell and useful targets for identifying new antimicrobial molecules which modulate, especially inhibit, E3 ligases.
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申请公布号 |
US2008261241(A1) |
申请公布日期 |
2008.10.23 |
申请号 |
US20070685122 |
申请日期 |
2007.03.12 |
申请人 |
INSTITUT PASTEUR;INSTITUT NAT. DE LA SANTE ET DE LA RECHERCHE MED.;MOUNT SINAI HOSPITAL |
发明人 |
ROY ROHDE JOHN;PARSOT CLAUDE RENE RAOUL;JOSEPH SANSONETTI PHILLIPPE |
分类号 |
G01N33/53;C12N1/14;C12N5/04;C12N5/06;C12N9/00;C12N15/00;C12N15/11;C12P21/04;C12Q1/00 |
主分类号 |
G01N33/53 |
代理机构 |
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主权项 |
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地址 |
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