MICROFLUIDIC SYSTEM WITH ACTUATORS

摘要

The invention relates to microfluidic system (100), particularly a biosensor, for manipulating a sample in a sample chamber (1). The device comprises at least one actuator (10) that reversibly changes its spatial configuration if it is heated and/or cooled. The actuator (10) may particularly be arranged adjacent to an associated heating element (20) of a 5 heating array that is used to establish a predetermined spatial and/or temporal temperature profile in the sample chamber (1). The configuration change of the actuator (10) can be used to move the sample fluid or to control its passage through fluid channels. A plurality of actuators (10) may optionally be provided that undergo their configuration changes at different temperatures, particularly temperatures within a range that is passed during a 10 reaction like PCR.