发明名称 DEUTERATED DERIVATIVES OF 4-(6-FLUORO-1, 2-BENZISOXAZOL-3-YL) PIPERIDINE COMPOUNDS
摘要 <p>This invention relates to novel 1, 2-benzisoxazol-3-yl compounds of formula (I), their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering an antagonist of both dopamine and serotonin receptors. (I), wherein:at least one R group (i.e., R&lt;SUP&gt;1a&lt;/SUP&gt;, R&lt;SUP&gt;1b&lt;/SUP&gt;, R&lt;SUP&gt;2&lt;/SUP&gt;, R&lt;SUP&gt;3a&lt;/SUP&gt;, and R&lt;SUP&gt;3b&lt;/SUP&gt;) comprises a deuterium atom.</p>
申请公布号 WO2008128166(A1) 申请公布日期 2008.10.23
申请号 WO2008US60210 申请日期 2008.04.14
申请人 CONCERT PHARMACEUTICALS INC.;HARBESON, SCOTT, L. 发明人 HARBESON, SCOTT, L.
分类号 C07D413/04;A61K31/423;A61P25/00 主分类号 C07D413/04
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