发明名称 |
Bispecific Fusion Antibodies With Enhanced Serum Half-Life |
摘要 |
Drug compositions, fusions and conjugates are provided. The drug fusions and conjugates contain a therapeutic or diagnostic agent that is fused or conjugated to an antigen-binding fragment of an antibody that binds serum albumin. The drug compositions, fusions and conjugates have a longer in vivo half-life in comparison with the unconjugated or unfused therapeutic or diagnostic agent.
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申请公布号 |
US2008260757(A1) |
申请公布日期 |
2008.10.23 |
申请号 |
US20050628149 |
申请日期 |
2005.05.31 |
申请人 |
DOMANTIS LIMITED |
发明人 |
HOLT LUCY J.;TOMLINSON IAN M. |
分类号 |
A61K39/44;A61K47/48;A61P29/00;C07H21/04;C07K16/00;C07K16/18;C07K16/46;C12N5/06;C12P21/02 |
主分类号 |
A61K39/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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