发明名称 |
STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS |
摘要 |
Stilbene derivatives exhibit killing and suppression of growth activity against a variety of cancer cells, and are effective at suppressing tumor growth in vivo. The stilbene derivatives may be used in the treatment of diseases characterized by cell hyperproliferation including human malignancies and non-malignant diseases such as liver cirrhosis. Stilbenes may also disrupt abnormal vessels in tumor to achieve vascular disrupting effect to suppress tumor growth. Water soluble pro-drug forms of stilbene derivatives are particularly useful in suppressing tumor growth in vivo.
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申请公布号 |
US2008261982(A1) |
申请公布日期 |
2008.10.23 |
申请号 |
US20070738813 |
申请日期 |
2007.04.23 |
申请人 |
LEE RUEY-MIN;SIMONI DANIELE |
发明人 |
LEE RUEY-MIN;SIMONI DANIELE |
分类号 |
A61K31/09;A61K31/136;A61K31/192;A61K31/27;A61K31/351;A61K31/4035;A61K31/4184;A61K31/5375;A61P35/00;C07C271/28;C07D295/15 |
主分类号 |
A61K31/09 |
代理机构 |
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