发明名称 |
Polypeptides for Oligomeric Assembly of Antigens |
摘要 |
A system for expressing antigenic polypeptides in oligomeric form fuses the antigenic polypeptide to an oligomerisation polypeptide such that the oligomerisation polypeptide can interact with other oligomerisation polypeptides and bring multiple copies of the antigenic polypeptide into close proximity in the form of an oligomer. Expressing the polypeptides in oligomeric form in this way can improve their immunogenicity compared to a monomeric form.
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申请公布号 |
US2008260769(A1) |
申请公布日期 |
2008.10.23 |
申请号 |
US20050632385 |
申请日期 |
2005.07.22 |
申请人 |
CAPECCHI BARBARA;MASIGNANI VEGA;RAPPUOLI RINO;SCARSELLI MARIA |
发明人 |
CAPECCHI BARBARA;MASIGNANI VEGA;RAPPUOLI RINO;SCARSELLI MARIA |
分类号 |
A61K39/02;A61K31/7088;A61K35/74;A61K38/00;C07H21/00;C07K2/00;C12N1/20 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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